Dexamethasone reduced the incidence of children with mild croup who returned for medical care.
نویسنده
چکیده
Bjornson CL, Klassen TP, Williamson J, et al; for the Pediatric Emergency Research Canada Network. A randomized trial of a single dose of oral dexamethasone for mild croup. N Engl J Med 2004;351:1306–13. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
منابع مشابه
A randomized trial of a single dose of oral dexamethasone for mild croup.
BACKGROUND The benefits of dexamethasone treatment for moderate-to-severe croup are well established. However, most children with croup have mild symptoms, and it is unknown whether they would derive the same degree of benefit from dexamethasone treatment as children with more severe disease. METHODS We conducted a double-blind trial at four pediatric emergency departments in which 720 childr...
متن کاملEffectiveness of oral or nebulized dexamethasone for children with mild croup.
OBJECTIVE To assess the efficacy of oral dexamethasone or nebulized dexamethasone sodium phosphate in children with mild croup. METHODS Double-blind, placebo-controlled study of 264 children between 6 months and 6 years of age with symptoms of croup for fewer than 48 hours. Patients were excluded if they received racemic epinephrine or corticosteroid treatment. Other exclusion criteria includ...
متن کاملCroup: assessment and evidence-based management.
Croup affects about 2% of preschool-aged children every year. Most children have mild croup and are managed at home, often after review by a general practitioner, who may decide that a single dose of oral corticosteroid is indicated (eg, if a risk factor for hospital admission exists). A minority of children develop moderate or severe croup. They should be reviewed in an emergency department an...
متن کاملOral dexamethasone led to fewer treatment failures than did nebulized dexamethasone or placebo in children with mild croup.
I n t e r v e n t i o n Children were allocated to oral dexamethasone, 0.6 mg/kg of body weight to a maximum dose of 10 mg, and nebulized placebo (n = 85); nebulized dexamethasone sodium phosphate, 160 μg (n = 91), and oral placebo; or oral and nebulized placebo (n = 88). M a i n o u t c o m e m e a s u r e s The primary outcome was treatment failure (re-evaluation leading to a prescription for...
متن کاملPediatric Pulmonology 20:362-368 (1995) Oral Dexamethasone in the Treatment of Croup: 0.15 mglkg Versus 0.3 mglkg Versus 0.6 mglkg
The objective of this study was to compare the efficacy of a single dose of oral dexamethasone of varying sizes in 120 children hospitalized with croup in two sequential double 'blind, randomized, controlled clinical trials (Trials A and B). The study was conducted in the Emergency Department Observation Ward of a tertiary pediatric hospital. One hundred and twenty children (age range 6 to 160 ...
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ورودعنوان ژورنال:
- Evidence-based nursing
دوره 8 2 شماره
صفحات -
تاریخ انتشار 2005